Moving from CBS for its first two years of production to first-run syndication, the new production company wanted to have the premise inserted into the opening titles so that first-time viewers wouldn't be confused as to what a Canadian Mountie was doing in Chicago. Not wanting to alter the opening titles, Paul Gross opted to simply state the premise in each episode with the line, "I first came to Chicago on the trail of the killers of my father, and for reasons that don't need exploring at this juncture I've remained, attached as liaison with the Canadian Consulate." This became a running gag throughout the third season, as the writers found various ways to insert the line in different ways into almost each script, whether it was spoken by Fraser or other supporting characters.

For a time, this was considered the most popular Canadian-based and produced TV series ever shown on a US network. After a break in production following the first two seasons, the producers were able to obtain international funding to continue production.

Fraser is named after the Fraser River in British Columbia, Canada. Diefenbaker is named after John Diefenbaker, Prime Minister of Canada, 1957-63. Thatcher is named after Margaret Thatcher, Prime Minister of the UK, 1979-90.

Leslie Nielsen, who played the recurring role of Canadian Mountie Buck Frobisher, is in real life the son of a Mountie.

Leslie Nielsen's recurring character - legendary mountie Buck Frobisher - was named for 16th century explorer Sir Martin Frobisher, who explorer the northern areas of what is now Canada searching for the Northwest Passage.

The license plate RCW139 appears on cars in a lot of the episodes from the seasons.

While Constable Fraser has sustained various injuries during the run of the series, they have only happened when he chose not to wear his hat, or it had been knocked off his head through various circumstances. This has earned his hat the nickname, "The Stetson of Invulnerability."

The leather bar in episodes 109 and 108 ("A Chicago Holiday" parts 1 and 2) is actually the set of The Raven, Janette's nightclub from the television series Forever Knight.

Stanley Kowalski and Stella Kowalski are character names taken from Tennessee Williams' "A Streetcar Named Desire".